Medicine, Università degli Studi di Firenze
I am a fifth-year medical student in Florence. My work runs along one question asked in two places: when is a process far enough along that we are entitled to call it something, and to act on it.
On the clinical side that is nosology — where a label starts, and what separates a disease from the damage that preceded it. On the quantitative side it is enzyme kinetics, where the same problem appears as the question of how to read a modulated state rather than report two numbers.
Drug Metabolism and Pharmacokinetics
Modulation of an enzyme is usually reported as a change in two parameters read separately. Here the modulated state is normalised against its own native control and read as a single point on a plane, where position carries the direction of the effect, its size, and an internal consistency check on the data behind it.
Structured tracking of physiological measurements, built so that what a patient records between visits arrives at their doctor in a form that can actually be read.
Put in a native and a modulated Km–Vmax pair and see the same displacement drawn four ways at once: saturation curve, Lineweaver–Burk, the catalytic plane, and the circle-and-triangle geometry.